Findings suggest that severe sepsis can lead to impairment of immune system
An analysis of lung and spleen tissue from patients who died of sepsis revealed certain biochemical, cellular and histological findings that were consistent with immunosuppression, according to a study...
View ArticleThe existence of neutrophils in the spleen discovered
For the first time, it has been discovered that neutrophils exist in the spleen without there being an infection. This important finding made by the research group on the Biology of B Cells of IMIM...
View ArticleNatural method for clearing cellular debris provides new targets for lupus...
Cells that die naturally generate a lot of internal debris that can trigger the immune system to attack the body, leading to diseases such as lupus.
View ArticleHow music prevents heart transplant rejection
Music has a fundamental affect on humans. It can reduce stress, enhance relaxation, provide a distraction from pain, and improve the results of clinical therapy. New research published in BioMed...
View ArticleResearchers discover first gene linked to missing spleen in newborns
Researchers at Weill Cornell Medical College and Rockefeller University have identified the first gene to be linked to a rare condition in which babies are born without a spleen, putting those children...
View ArticleSuccessful transplantation of tissue-engineered vein in a child offers hope
The first biologically tissue-engineered vein grown from a patient's own stem cells has been successfully transplanted into a 10-year-old girl with portal vein obstruction, dramatically enhancing her...
View ArticleStudy finds one treatment stands above others for adults with Langerhans cell...
A study by a Baylor College of Medicine physician-researcher has shed light on the most effective treatment for adults with Langerhans cell histiocytosis (LCH) in bones. LCH is a disease that can...
View ArticleImmune system protein could explain pancreatitis
It is likely that the protein is also highly significant for other inflammatory diseases.
View ArticleEU approves Novartis-Incyte blood cancer drug
Novartis AG and Incyte Corp. said Tuesday that European Union regulators approved their blood cancer drug Jakavi.
View ArticleNew Otago collaboration brings oral TB vaccine for humans closer
Researchers in New Zealand are inching closer to the development of the first effective oral vaccine to protect against tuberculosis - a disease which still kills more people worldwide than any other...
View ArticleCombination therapy using JAK2 and HSP90 inhibitors increased efficacy in...
Researchers have demonstrated that combination therapy with PU-H71 and ruxolitinib increases the durability and effectiveness of a treatment that had previously shown limited utility for patients with...
View ArticleTransplanted genetically-modified adipose cells offer potential therapy for...
Using mesenchymal stromal cells derived from adipose (fat) tissues, genetically modified to express a bioluminescent marker, researchers in Italy have tracked cells after transplantation. The cells...
View ArticleGenetics discovery to help fight 'black fever'
Scientists—including a geneticist at The University of Western Australia—are a step closer to developing a vaccine against a fatally infectious parasite carried in the bite of sandflies.
View ArticleCerebral malaria: Pinpointing a potential therapeutic target
An excessive response of the immune system to malarial infection can lead to serious complications, such as cerebral malaria. While the mechanism causing the onset of cerebral malaria is unclear,...
View ArticleResearchers find that simple blood test can help identify trauma patients at...
A simple, inexpensive blood test performed on trauma patients upon admission can help doctors easily identify patients at greatest risk of death, according to a new study by researchers at...
View ArticleEpigenetic marker 5hmC opens door to studying its role in developmental...
Nearly every cell in the human body carries a copy of the full human genome. So how is it that the cells that detect light in the human eye are so different from those of, say, the beating heart or the...
View ArticleHow the immune system positions its gatekeepers
(Medical Xpress)—For an immune response to get underway, an invading microbe must first be halted in the spleen, and then digested by immune cells known as 'dendritic cells', which guard specific...
View ArticleScientists discover gene mutation that causes children to be born without spleen
The spleen is rarely noticed, until it is missing. In children born without this organ, that doesn't happen until they become sick with life-threatening bacterial infections. An international team of...
View ArticleHow to create useful knowledge from pure data
Imagine a hospital where patient data from numerous sources is made accessible to ward physicians with the help of hyperlinks and intelligent indexing. Imagine a healthcare system that hands its...
View ArticleShort-term antidepressant use, stress, high-fat diet linked to long-term...
Short-term use of antidepressants, combined with stress and a high-fat diet, is associated with long-term increases in body weight, a new animal study finds. The results were presented Sunday at The...
View ArticleStudy tracks risk of VL exposure in Brazil's urban areas
Visceral Leishmaniasis (VL) is a severe chronic systemic disease caused by the protozoa (Leishmania infantum) in South America, the Mediterranean, southwest and central Asia. These parasites lodges in...
View ArticleFDA approves new drug for rare genetic disease
The Food and Drug Administration has approved a new capsule-based drug to treat Gaucher's disease.
View ArticlePregnant sheep considered in pre-term birth study
Scientists are a step closer to understanding how bacterial infections in pregnant women lead to pre-term births—the main cause of neonatal death and disease in Australia.
View ArticleTeam identifies emergency response system for blood formation
Scientists at the Children's Medical Center Research Institute at UT Southwestern (CRI) have determined how the body responds during times of emergency when it needs more blood cells. In a study...
View ArticleSplenomegaly ups thrombosis in essential thrombocythemia
(HealthDay)—In patients with essential thrombocythemia (ET), baseline splenomegaly is associated with increased risk of thrombosis, according to a study published online Jan. 7 in the American Journal...
View ArticleItaly swaps spleen for kidney in world first
A hospital in northern Italy said Wednesday it had achieved a world first by successfully transplanting a kidney in the place of the spleen in a six-year-old girl.
View ArticleNeural crest cells contribute an astrocyte-like glial population to the spleen
Neural crest cells (NCC) are multi-potent cells of ectodermal origin that colonize diverse organs, including the gastrointestinal tract to form the enteric nervous system (ENS) and hematopoietic organs...
View ArticleResearchers unlock clues to how cells move through the body
During its 120-day cycle the circulatory system transports red blood cells and nutrients throughout the human body. This system helps keep the body in balance and fight against infections and diseases...
View ArticleSeven body organs you can live without
The human body is incredibly resilient. When you donate a pint of blood, you lose about 3.5 trillion red blood cells, but your body quickly replaces them. You can even lose large chunks of vital organs...
View ArticleNew technique reduces side-effects, improves delivery of chemotherapy nanodrugs
Carnegie Mellon University researchers have developed a new method for delivering chemotherapy nanodrugs that increases the drugs' bioavailability and reduces side-effects.
View Article